Research Associate II/Sr. Research Associate – Surface Chemistry

Company Overview

Sarmal, Inc. is a San Diego–based biotechnology company developing next-generation genomics and molecular detection platforms. Our work integrates molecular biology, chemistry, and advanced systems engineering to enable faster, more precise, and more accessible genomic insights. 
 
We are a highly collaborative, R&D-driven team operating in a fast-paced, early-stage environment. Our scientists and engineers work across disciplines to solve complex technical challenges and translate innovation into scalable, real-world applications. 
 
At Sarmal, we value scientific rigor, curiosity, and a builder mindset. We are looking for individuals who are energized by ambiguity, motivated by impact, and excited to help bring breakthrough technologies from concept to reality.

• Execute surface functionalization batch runs (SAM, silane, hydrogel, brush polymer chemistries) per written SOPs/batch records, working independently after initial onboarding.

• Independently operate the team's core surface characterization methods — fluorescence-based uniformity assays, contact angle, and EIS/CV — for routine batch and process characterization.

• Summarize characterization results (thickness, density, uniformity, charge) and flag trends relevant to assay performance (signal, specificity, non-specific binding) for scientist review.

• Support development of nucleotide-based assay consumables and other biofunctionalized surface work (e.g., oligonucleotide/probe immobilization, hybridization assays, bioconjugation in microarray/biointerface contexts).

• Assist with surface deposition/patterning process runs (spin-coating, dip-coating, spray-coating, plasma treatment/activation; exposure to PE-CVD/CVD or photolithographic patterning a plus).

• Execute DOE test plans designed by scientists, applying basic statistical analysis (ANOVA, regression, or similar) to interpret and summarize results; input into test design as experience builds.

• Log data accurately and promptly in lab notebooks/ELN; flag and help investigate deviations from expected process parameters.

• Maintain organized inventory of chemistry consumables and reagents used in daily runs.

• Maintain cleanroom/lab space per site protocols.

• Work collaboratively with in-house scientists; expected to troubleshoot routine issues independently and escalate non-routine ones.

• Hands-on experience working with interfacial materials (2D surface, microarray, flow cell, nanoparticle, membranes, etc.) and executing relevant analytical methods e.g. fluorescence-based uniformity assays, goniometry, etc.

• Familiarity with nucleotide-based assay chemistries or other biofunctionalized surfaces (e.g., oligonucleotide/probe immobilization, hybridization assays, bioconjugation in microarray/biointerface contexts).

• Demonstrated track record of independent, precise batch/production execution within a structured process or manufacturing pipeline.

• Working knowledge of DOE fundamentals and basic statistical analysis, sufficient to execute and interpret a senior-designed test plan.

• Comfort with structured documentation (batch records, ELN, GDP-style recordkeeping).